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Bowel and Uterine Cancers

Gene changes and the risk of Bowel & Uterine Cancer

Approximately 1 in 21 people will develop bowel cancer during their lifetime. It is uncommon before the age of 40, and is slightly more common among men than women.

Bowel Cancer

When your medical practitioner talks about bowel cancer (also known as colorectal cancer) they are referring to cancer of the colon or rectum.


Age and health history can affect the risk of developing bowel cancer. If you have a family history of bowel cancer, it is advisable to have regular checkups and you should consult your medical practitioner... read more.

Uterine Cancer

In addition, for women carrying a change in one of the mismatch repair genes (MLH1, MSH2 or MSH6) mentioned above, the risk of contracting uterine cancer may be as high as 71%. Uterine cancer is the most common type of gynaecological cancer affecting women.

Changes in these genes are also associated with bowel and uterine cancer occurring at significantly younger ages than usual (on average 25 years earlier than the general population).

Genetic testing for bowel and/or uterine cancer involves looking for an inherited change (sometimes called a mutation) in one of the above genes. Testing is performed using a small blood sample.

Further information:

If you are concerned about your cancer risk and would like to know more about genetic testing for bowel and uterine cancer, please contact your medical practitioner.

For details on ordering the genetic testing for bowel and/or uterine cancer please click here.

Please click here to read how to have the test done.

For details of a genetic service in your area, contact Genetic Technologies or click here for a detailed list.

Download our genetic testing brochure for cancer


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